| 254 | V Sehwag | India v Pakistan at Lahore, 1st Test, 13/01/2006 [1781] |
| 199 | Younis Khan | Pakistan v India at Lahore, 1st Test, 13/01/2006 [1781] |
| 194 | Younis Khan | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 173 | Mohammad Yousuf | Pakistan v India at Lahore, 1st Test, 13/01/2006 [1781] |
| 156 | Shahid Afridi | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 148 | MS Dhoni | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 139 | Faisal Iqbal | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 128* | R Dravid | India v Pakistan at Lahore, 1st Test, 13/01/2006 [1781] |
| 126 | Mohammad Yousuf | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 122 | Yuvraj Singh | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 119 | Inzamam-ul-Haq | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 113 | Kamran Akmal | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 103 | Shahid Afridi | Pakistan v India at Lahore, 1st Test, 13/01/2006 [1781] |
| 103 | R Dravid | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 102* | Kamran Akmal | Pakistan v India at Lahore, 1st Test, 13/01/2006 [1781] |
| 97 | Mohammad Yousuf | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 90 | VVS Laxman | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 90 | IK Pathan | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 90 | Abdul Razzaq | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 83 | Younis Khan | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 78 | Kamran Akmal | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 77 | Younis Khan | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 65 | Mohammad Yousuf | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 60 | Shahid Afridi | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 59 | Shoaib Malik | Pakistan v India at Lahore, 1st Test, 13/01/2006 [1781] |
| 57 | Imran Farhat | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 53 | Salman Butt | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 47 | Shoaib Akhtar | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 45 | Abdul Razzaq | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 45 | Shoaib Akhtar | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 45 | Yuvraj Singh | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 40 | IK Pathan | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 38 | Harbhajan Singh | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 37 | Salman Butt | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 37 | Abdul Razzaq | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 37 | SC Ganguly | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 34 | SC Ganguly | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 32 | Abdul Razzaq | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 31 | V Sehwag | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 26 | SR Tendulkar | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 24 | Salman Butt | Pakistan v India at Faisalabad, 2nd Test, 21/01/2006 [1782] |
| 23 | SR Tendulkar | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 22 | Imran Farhat | Pakistan v India at Karachi, 3rd Test, 29/01/2006 [1783] |
| 21 | VVS Laxman | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 21 | Z Khan | India v Pakistan at Karachi, 3rd Test, 29/01/2006 [1783] |
| 20* | Z Khan | India v Pakistan at Faisalabad, 2nd Test, 21/01/2006 [1782] |
